OsteoFrax™
OsteoFrax™
OsteoFrax™ is an advanced bone health formula featuring patented botanicals and clinically studied nutrients designed to support stronger bones, healthy bone formation, and mobility to stay strong and active at any age.*
- Supports healthy bone turnover and remodeling to help maintain strong, resilient bones.*
- Features clinically studied OsteoCaf® + Calzbone®, patented botanicals selected to support bone strength and mobility.*
- Provides Vitamin D3 + K2 MK-7 (MenaQ7®) to support calcium absorption and proper nutrient utilization.*
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Supplement Facts
Supplement Facts
| Ingredient | Amount Per Serving | % Daily Values |
|---|---|---|
| Vitamin D3 (as Cholecalciferol) | 50 mcg (2000 IU) | 250% |
| Calzbone® Winged Treebine Stem Extract (Cissus quadrangularis) | 750 mg | ** |
| OsteoCaf® Indian Rosewood Extract (Dalbergia sissoo) | 500 mg | ** |
| Vitamin K2 (as Menaquinone-7 from MenaQ7®) | 100 mcg | ** |
**Daily Value not established.
Other Ingredients: Microcrystalline cellulose, hypromellose (capsule)
As seen on
The Bigger Picture:
How Bones Build, Remodel & Renew
Bones are living tissue, constantly undergoing a natural process called bone remodeling.
Throughout life, the body breaks down older bone tissue and replaces it with new bone tissue to maintain a healthy skeletal structure.
As we age, supporting healthy bone formation and balanced remodeling becomes increasingly important.
OsteoFrax™ combines specialized botanical extracts and essential nutrients to support these natural processes and help maintain strong, healthy bones.*
The OsteoFrax™ System:
4 Powerful Ingredients. 4 Essential Roles in Bone Health.
From calcium absorption and protein activation to bone formation and remodeling, OsteoFrax™ brings together four targeted ingredients to support healthy bones.*
absorb
Vitamin D₃ — 2,000 IU
- Helps absorb calcium.*
- Vitamin D₃ helps the body absorb calcium and supports healthy bone mineralization and normal muscle function.*
Activate
Vitamin K₂
MK-7 from MenaQ7® (100 mcg)- Activates bone- and vascular-health-related proteins.*
- Vitamin K₂ activates key proteins that support healthy bone mineralization and help protect against unwanted calcium buildup in arteries and other soft tissues.*
Form
OsteoCaf®
Dalbergia sissoo (500 mg)- Supports healthy bone formation.*
- A standardized botanical extract supported by clinical research on bone density, bone metabolism, and bone turnover markers.*
MAINTAIN
Calzbone®
Cissus quadrangularis (750 mg)- Supports bone maintenance and remodeling.*
- A clinically studied botanical with human research on bone density and skeletal health.*
Built for Stronger Bone Health & Everyday Living
Proactive bone health
For adults looking to take a proactive approach to maintaining healthy bones as they age.*
Active adults
Supports normal bone metabolism as part of an active lifestyle that includes regular exercise and balanced nutrition.*
Bone formation & remodeling
Supports the natural processes involved in forming and maintaining healthy bone tissue.*
Healthy aging
Targeted nutritional support for maintaining long-term skeletal health and an active lifestyle.*
A Message from
Bone Coach® Kevin Ellis
“Most of the people in our 300,000+ person bone health community are trying to stay active and protect their independence.
What I love about OsteoFrax™ is that it combines two specialized botanical extracts with essential bone-support nutrients in one targeted bone support formula.
It's designed to complement the foundational steps we teach for maintaining healthy bones, including proper nutrition and exercise.
Because strong bones aren't just about today. They're about supporting the strength and independence to enjoy life for years to come.”
Kevin Ellis, Bone Coach®
Founder & CEO, Healthy Bones Co.
Quality You Can Trust
Carefully selected ingredients, transparent labeling, and a commitment to quality in every serving.
Gluten
Free
Sugar
Free
Dairy
free
NON
GMO
Third-party
tested
GMP Certified
facility
manufactured in the USA
Frequently Asked Questions
OsteoFrax™ is an advanced bone-health supplement combining two clinically studied botanical extracts—OsteoCaf® and Calzbone®—with vitamins D₃ and K₂.
Together, these ingredients support calcium absorption, normal bone metabolism, healthy bone formation, and long-term skeletal health.*
OsteoFrax™ provides four targeted ingredients with complementary roles:
- Vitamin D₃: Helps the body absorb calcium.*
- Vitamin K₂: Supports the activation of proteins involved in normal bone mineralization and calcium regulation.*
- OsteoCaf®: Supports healthy bone formation.*
- Calzbone®: Supports bone maintenance and remodeling.*
Together, they provide targeted nutritional support for maintaining healthy bones.*
OsteoFrax™ is designed for adults who want to proactively support their bone health, particularly as they age.
It's a convenient addition to a comprehensive bone-health routine that includes adequate nutrition, appropriate exercise, and healthy lifestyle habits.
Many traditional bone supplements focus primarily on providing calcium and Vitamin D.
OsteoFrax™ takes a different approach by combining two specialized botanical extracts—OsteoCaf® and Calzbone®—with vitamins D₃ and K₂.
This combination provides targeted support for calcium absorption, bone formation, and normal bone remodeling.*
Take four capsules daily with a meal, or as directed by a healthcare provider.
Consistency is important when incorporating a supplement into a long-term bone-health routine.
OsteoFrax™ is designed for consistent daily use as part of a long-term approach to maintaining healthy bones.
Bone remodeling is an ongoing biological process, and supporting skeletal health involves consistent nutrition, physical activity, and other healthy lifestyle habits.
Yes! OsteoFrax™ is manufactured in the USA using globally sourced ingredients, is third party tested, and is formulated with carefully selected botanical extracts and essential nutrients.
Medical Disclaimer:
The information shared above is for informational purposes only and is not intended to provide medical or nutrition therapy advice; it does not diagnose, treat or cure any disease, condition; it is not to be used as a replacement or substitute for medical advice provided by physicians and trained medical professionals.
If you are under the care of a healthcare professional or are currently using prescription medications, you should discuss any dietary and lifestyle changes or potential dietary supplements use with your doctor. You should not discontinue any prescription medications without first consulting your doctor.
FDA Disclaimer:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. The content of this blog is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard, or delay in obtaining, medical advice for any medical condition they may have, and should seek the assistance of their health care professionals for any such conditions.
You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.
Dalbergia Sissoo References
- Raut AA, Meeta, Vaidya AD, et al. A clinical study of a standardized extract of leaves of Dalbergia sissoo (Roxb ex DC) in postmenopausal osteoporosis. Journal of Mid-Life Health. 2019;10(1):37–42.
- Dixit P, Pande S, Deshmukh A. Safety and efficacy of a standardized extract from leaves of Dalbergia sissoo in healing of long-bone fracture: A pilot clinical study. Journal of Complementary Medicine & Alternative Healthcare. 2018;5(1):JCMAH.MS.ID.555654.
- PG G, Chugh A, Chaudhry K, et al. Comparison of Teriparatide and Combination of Cissus quadrangularis and Dalbergia sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-Label Control Trial. Craniomaxillofacial Trauma & Reconstruction. 2023;16(1):23–33.
- Ahmad, N., Gautam, J., Singh, A., et al. (2014). A novel therapeutic approach with Caviunin-based isoflavonoid that en routes bone marrow cells to bone formation via BMP2/Wnt-β-catenin signaling. Cell Death & Disease, 5(9), e1427.
- Dixit, P., Mittal, P., Sharma, R., et al. (2012). Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity. Bioorganic & Medicinal Chemistry Letters, 22(2), 890–897.
- Khedgikar, V., Ahmad, N., Gautam, J., et al. (2012). A standardized phytopreparation from an Indian medicinal plant (Dalbergia sissoo) has antiresorptive and bone-forming effects on a postmenopausal osteoporosis model of rat. Menopause, 19(12), 1336–1346.
- Khedgikar, V., Ahmad, N., Trivedi, R., et al. (2017). Ethanolic extract of Dalbergia sissoo promotes rapid regeneration of cortical bone in drill-hole defect model of rat. Biomedicine & Pharmacotherapy, 86, 16–22.
- Miranda, L. L., Gomes, F. O., de Almeida, J. C., et al. (2019). Plant Extracts in the Bone Repair Process: A Systematic Review. Frontiers in Pharmacology, 10, 1347.
Cissus Quadrangularis References
- Brahmkshatriya, H. R., Jadav, P. K., Brahmkshatriya, M. H., & Shah, H. A. (2015). Clinical evaluation of Cissus quadrangularis as osteogenic agent in maxillofacial fracture: A pilot study. Ayu, 36(2), 169–173.
- Deshmukh, V. S., Khot, R. S., Thawani, V. R., Abichandani, L. G., & Goswami, S. S. (2011). Efficacy of Cissus quadrangularis in perimenopausal low bone density women. The Antiseptic, 108(10), 504–506.
- Dhatrak, S., Thawani, V., Gharpure, K., Apte, I., Masand, A., Hingorani, L., & Khiyani, R. (2011). Effect of herbal combination in low bone mass density patients. International Journal of Drug Discovery and Technology, 2(1), 9–14.
- Singh, N., Singh, V., Singh, R. K., Pant, A. B., Pal, U. S., Malkunje, L. R., & Mehta, G. (2013). Osteogenic potential of Cissus quadrangularis assessed with osteopontin expression. National Journal of Maxillofacial Surgery, 4(1), 52–56.
- Singh, V., Gupta, V., Sharma, R., Singh, R., & Singh, G. (2011). Clinical evaluation of Cissus quadrangularis and Moringa oleifera as osteogenic agents in mandibular fractures. Journal of Maxillofacial and Oral Surgery, 10(1), 6–11.
- Stohs, S. J., & Ray, S. D. (2013). A review and evaluation of the efficacy and safety of Cissus quadrangularis extracts. Phytotherapy Research, 27(8), 1107–1114.
- Takuathung, M. N., Mekseepralard, C., Ingkaninan, K., Sawangjit, R., & Jampachaisri, K. (2024). The effects of Cissus quadrangularis on bone-related biomarkers in humans: A systematic review and meta-analysis. Frontiers in Nutrition, 11, 12288206.
- Thawani, V., Kimmtakar, N., Hingorani, L., & Khiyani, R. (2002). Effect of herbal combination containing Cissus quadrangularis in fracture healing. The Antiseptic, 99(9), 345–347.
- Udupa, K. N., & Prasad, G. C. (1962). Cissus quadrangularis in healing of fractures. A clinical study. Journal of the Indian Medical Association, 38(12), 590–593.
- Udupa, K. N., & Prasad, G. C. (1964). Further studies on the effect of Cissus quadrangularis in accelerating fracture healing. Indian Journal of Medical Research, 52(1), 26–35.
- Cissus quadrangularis in bone healing and oxidative stress. (2024). Journal of Advances in Medicine and Pharmaceutical Sciences, 3(1), 1–10.
Vitamin K2 MK-7 References
- Knapen MHJ, Drummen NE, Smit E, Vermeer C, Theuwissen E. Osteoporos Int. 2013;24(9):2499–2507.
- Kanellakis S, Moschonis G, Tenta R, et al. Calcif Tissue Int. 2012;90(4):251–262.
- Theuwissen E, Cranenburg EC, Knapen MHJ, et al. Br J Nutr. 2012;108(9):1652–1657.
- Knapen MHJ, Gijsbers BL, et al. J Nutr Sci. 2015;4:e35.
- van Summeren MJ, et al. Br J Nutr. 2009;102(8):1171–1178.