The ingredients in Annatrol™ have decades of research behind them and multiple double-blind, randomized controlled trials showing their benefits.
- Maintenance of healthy muscles and bones during aging*
- Helps maintain skin, eye, and bone health*
- Promotes cardiovascular, circulatory health, and a healthy lipid profile*
- Promotes regulation of healthy metabolic functioning*
- Insulin sensitivity and normal glycemic control*
- A healthy inflammatory response*
- Antioxidant status*
- Healthy liver function*
- Mitochondrial function and cellular energy generation*
- Hormone synthesis*
- Proper cell membrane construction*
- Supports antioxidant activity*
- Provides support for healthy total cholesterol levels as well as LDL cholesterol levels within the normal range*
The ingredients in Annatrol™ are backed by studies including:
- In an open label, dose escalation study, 250mg/day of annatto tocotrienols improved lipid parameters, inflammatory biomarkers, and oxidative stress in hypercholesterolemia subjects.
- In a randomized, double-blind, placebo-controlled study, 300mg of annatto tocotrienols decreased bone resorption, and improved bone turnover rate in postmenopausal women.
- In a randomized, double-blind, placebo-controlled study, 250mg/day of annatto tocotrienols led to improved glycemic control accompanied by reduced inflammation, and oxidative stress, and further confirmed by modified miRNA expression.
- In a randomized, double-blind, placebo-controlled study, 300mg of annatto tocotrienols improved glycemic control in patients with prediabetes.
The annatto tree, native to Latin America, is the source for the tocotrienols and geranylgeraniol in Annatrol™.
Tocotrienols (T3) are components of the vitamin E complex that have distinct biochemical properties not observed with the more commonly known tocopherol fractions. Annatto is the richest known source of naturally occurring T3 and is virtually free of tocopherols, containing nearly 100% T3. Tocotrienols have shown impressive effects in supporting cardiovascular health, including supporting healthy cholesterol and triglyceride levels and promoting a healthy inflammatory response. Owing to their positive influence on lipids (fats in the blood), T3 may be beneficial for those with a buildup of fat in the liver, as well as those who need help maintaining normal blood sugar and insulin levels. New research also suggests tocotrienols may be useful for supporting strong, healthy bones.*
Geranylgeraniol (GG) is found in annatto as well. It is also synthesized internally in humans but this production declines naturally during aging and is often inadequate to support the body’s needs. Additionally, synthesis of GG is inhibited by use of certain pharmaceutical drugs commonly prescribed for the aging population (such as those used to treat osteoporosis). Geranylgeraniol (GG) is needed for constructing cell membranes, producing energy in mitochondria, supporting the production of hormones (such as testosterone), proper calcium trafficking (depositing calcium in the bones and teeth and keeping it out of other tissues, such as blood vessels and joints), and more. It is needed for protein synthesis and modification—helping to build proteins and have them perform their functions efficiently.*
Take 2 softgels per day, or as directed by your health-care practitioner.
