Osteoporosis & Oral Health Decline
Discover How Protecting Your Smile Can Also Protect Your Bones.
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Imagine sitting in the dentist’s chair…
Mouth open…
Eagerly awaiting the verdict on the state of your oral health…
Another cavity?
Root canal?
Gum disease?
Jaw necrosis?
Infection?
Or a tooth on the brink of failing right in the middle of your beautiful smile?
Even with diligent oral care, our later years see a rise in dental decline… despite our best efforts.
The same is true for our bones…
We try to eat healthy…
We exercise…
We feel like we’re doing all the right things...
Then we get told we have osteoporosis.
What many people don’t realize is…
There is a connection between osteoporosis and your oral health.
Weak teeth can mean weak bones and vice versa.
How do we know this?
Well, there are a few ways…
First, there’s a specific portion of our jawbone that contains the tooth sockets known as the alveolar process.
When the alveolar process loses bone density, we become more susceptible to a number of oral health issues (1), including:
Loose teeth
Tooth loss
Periodontal/gum disease
Second, the National Institutes of Health found the effect of osteoporosis on the alveolar process to be so pronounced that women with osteoporosis are more than three times as likely to experience tooth loss than women without osteoporosis (2).
Research published in the Journal of Mid-Health also found those with osteoporosis had significantly higher rates of tooth loss (3).
For those with osteoporosis taking antiresorptive medications like Bisphosphonates or Prolia®, especially for multiple years, there is a risk for osteonecrosis of the jaw (ONJ)—when cells within the jaw start to die.
Finally, gum disease and periodontitis can lead to the body’s own immune system attacking and destroying the bone structure that supports your teeth (4).
It's kind of scary to hear that osteoporosis is connected to tooth loss and oral health decline...
But the good news is, there is something you can do to support your teeth and your bones...
And it's one of the easiest, safest, most powerful, natural interventions you can make...
Backed by plenty of good research.
But before I tell you about what that is...
I want to tell you that I'm no stranger to issues with my teeth.
Throughout my life, I experienced bone loss, cavities, root canals, and oral health issues.
Partly because I didn't have the best diet and nutrition growing up (lots of candy, sugary soft drinks, not a lot of leafy greens)...
Partly due to other lifestyle factors that led to bone loss (high stress, poor sleep, chronic digestive issues)…
And partly because when I was in the Marine Corps, I suffered trauma to the left side of my face that caused microcracks and fractures in multiple teeth. All of those things led to four separate root canals in the back left side of my mouth.
Eventually, all of those root canals became infected and stayed infected for years.
The Biggest Concern: Bacteria traveling through the bloodstream to my heart where they could multiply, produce toxins, and become life-threatening.
Extraction of those infected teeth was the only option.
So, I scheduled the appointment...
The procedure itself took over 9 hours and cost more than $20,000 (not covered by insurance).
That was just for the first appointment and didn’t cover any implants which are upwards of $5,000+ per tooth!
I was also in pretty significant pain for about 10 days after the procedure…
And I was concerned I may end up losing other teeth because of the trauma from four extractions at the same time.
It was a tough decision to make, but it needed to be made for me to have a healthy mouth and a healthy heart.
I don't ever want to go through that process again...
And I certainly don't want you to have to go through it if you don’t have to…
The pain.
The risk.
The tens of thousands of dollars spent.
I’d rather help you stop your oral health decline in its tracks.
Obviously, improving nutrition, lifestyle, and avoiding trauma to the mouth can help...
But oftentimes that's just not enough.
That's why you need to learn about Geranylgeraniol (GG)
First, let me explain what Geranygeraniol is…
Geranylgeraniol (GG) is a lesser-known compound that occurs naturally in smaller amounts in various foods like castor oil, flax seeds, carrots, tomatoes, and olive oil.
But, the majority of GG is made in our bodies (endogenously) via the mevalonate pathway...
This is the same biochemical pathway by which cholesterol, steroid hormones, ubiquinone (CoQ10) and vitamin K2 MK-4 are synthesized.
Why does GG matter?
GG is an essential building block for our health: our teeth, bones, muscles, hormones, energy levels, temperature control, pain management, and more require it.
We need GG for protein synthesis.
We need GG for healthy mitochondrial function and the generation of ATP for energy.
We need GG for the production of testosterone, progesterone, CoQ10, and vitamin K2-MK4.
K2 MK-4 is the primary form of vitamin K2 found in our bodies and is crucial for managing calcium transport, especially to the bones.
You can see just how important GG is.
But here’s the thing…
GG production declines as we age and is inhibited by the use of statins and bisphosphonates.
So, as you get older…
And especially if you’re taking statin and bisphosphonates medications…
You need to be aware that you are inhibiting GG production further and your need for GG replenishment becomes greater.
Groundbreaking Studies Show GG
Benefits For Oral Health.
Now, let’s bring this full circle from where we started.
We know osteoporosis is connected to tooth loss and oral health decline…
You know it’s much more effective and way less costly to prevent oral health issues than to react to them…
That’s why you need to see these groundbreaking studies showing Geranylgeraniol’s role in helping improve oral health:
STUDY 1
Study 1 showed Geranylgeraniol (GG) improving bone in tooth sockets and restoring bone deposition (5).
STUDY 2
Study 2 showed GG reducing Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) Damage including preventing jaw necrosis (2.5x) and preventing gum death (3.5x)(6).
STUDY 3 & 4
Studies 3 and 4 showed Geranylgeraniol helped seal empty tooth sockets by 45% and improved gum vascularity, osteoblast lining, and epithelial coverage by 67% (7,8).
It's exciting and promising to see this research, and in time we may come to realize even greater benefit in humans!`
How much Geranylgeraniol (GG) do I need?
GG is one of the easiest, safest, most powerful, natural interventions you can make…
The benefits for most applications of GG start at around 150mg/day for bone health, oral health, CoQ10 replenishment, muscle tone and balance...
And go up to 300/mg day for those on Statin & Bisphosphonate medications (or if you've used them in the past) and for helping prevent myopathy and sarcopenia (age-related progressive loss of muscle mass and strength).**
By Replenishing Natural Levels, GG Can Help Promote
A Healthier Mouth, Stronger Bones, And A Better Body.
Where to get GG (there’s only one place)...
Because I knew just how important this was for our community with osteoporosis…
I worked directly with Dr. Barrie Tan, a distinguished scientist and the world’s leading expert in GG & Vitamin E research, to develop a pure and premium product for your health called Annatrol™ Bone Support.
Healthy Bones Co. Annatrol™ Bone Support
is a first of its kind combination of 300mg Geranylgeraniol (GG) and 300mg Annatto Tocotrienols – two powerful nutrients that support oral health, healthy aging, cellular energy generation, a healthy inflammatory response, heart health, and bone health.**
Why add 300mg of Annatto Tocotrienols with GG?
Annatto Tocotrienols are a form of Vitamin E shown to help support cardiovascular health, inflammatory biomarkers, healthy cholesterol levels, glycemic control, bone health, and metabolic health** with multiple randomized, double-blind controlled trials reinforcing its benefits:
Bone Health Study
In a randomized, double-blind, placebo-controlled study, 300mg of annatto tocotrienols decreased bone resorption, and improved bone formation in postmenopausal women. (9)
Cholesterol & Inflammation Study:
In an open label, dose escalation study, 250mg/day of annatto tocotrienols improved lipid parameters, inflammatory biomarkers, and oxidative stress in hypercholesterolemia subjects (10)
Glycemic Control Study
In a randomized, double-blind, placebo-controlled study, 250mg/day of annatto tocotrienols led to improved glycemic control accompanied by reduced inflammation, and oxidative stress, and further confirmed by modified miRNA expression. (11)
Prediabetes Study
In a randomized, double-blind, placebo-controlled study, 300mg of annatto tocotrienols improved glycemic control in patients with prediabetes. (12)
Strength, Blood Sugar, Cholesterol, Healthy Inflammatory Response, Energy & More Backed By 30 Years Of Research, In Just Two Daily Pea-Sized Capsules
Replenish your GG levels & reap the bone and health benefits of Tocotrienols today
There aren't many things you can take every single day with this level of well-documented health benefits without side effects.
We've added these two natural, safe, powerful and effective nutrients into two, tiny, pea-sized capsules that you can take daily!
This is one thing I personally take daily and make sure my wife and my mother do too.
Just 3 months of use could lead to the same significant benefits.
To living fearlessly and smiling confidently,
Kevin Ellis, Bone Coach®
CEO & Founder, Healthy Bones Co.
P.S. Send this page to everyone you know with oral health issues, osteoporosis, or who are on statins or bisphosphonates... They need this education!
P.P.S. Add Healthy Bones Co. Special & Specific Bioactive Collagen Peptides to your order for a powerful combination!
Get 10% Off Annatrol™ Bone Support
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Scientific References
References
General References
- Source: "Oral Health and Bone Disease | NIH Osteoporosis and Related .... "https://www.bones.nih(.)gov/health-info/bone/bone-health/oral-health/oral-health-and-bone-disease.
- Source: "Association between Dental Health and Osteoporosis: A Study in ...." https://www.ncbi.nlm.nih(.)gov/pmc/articles/PMC5753495/.
- Source: "Periodontitis - Symptoms and causes - Mayo Clinic." 14 Feb. 2020, https://www.mayoclinic(.)org/diseases-conditions/periodontitis/symptoms-causes/syc-20354473.
- Source: “Association between Dental Health and Osteoporosis: A Study in ....” https://journals.lww.com/jomh/fulltext/2017/08040/association_between_dental_health_and.2.aspx
Tocotrienol References
- Qureshi, A. A., Khan, D. A., Mahjabeen, W., & Qureshi, N. (2014). Dose-dependent Modulation of Lipid Parameters, Cytokines and RNA by δ-tocotrienol in Hypercholesterolemic Subjects Restricted to AHA Step-1 Diet. Journal of Advances in Medicine and Medical Research, 6(4), 351–366. doi:10.9734/BJMMR/2015/13820
- Shen CL, Yang S, Tomison MD, Romero AW, Felton CK, Mo H. Tocotrienol supplementation suppressed bone resorption and oxidative stress in postmenopausal osteopenic women: a 12-week randomized double-blinded placebo-controlled trial. Osteoporos Int. 2018;29(4):881-891. doi:10.1007/s00198-017-4356-x
- Mahjabeen W, Khan DA, Mirza SA, Pervez MA. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial. Phytother Res. 2021;35(7):3968-3976. doi:10.1002/ptr.7113
- Suleman F, Khan DA, Pervez MA, Aamir M. Effects of delta-tocotrienol supplementation on glycaemic control in individuals with prediabetes: A randomized controlled study. J Pak Med Assoc. 2022;72(1):4-7. doi:10.47391/JPMA.966
- Shen CL, Mo H, Dunn DM, Watkins BA. Tocotrienol Supplementation Led to Higher Serum Levels of Lysophospholipids but Lower Acylcarnitines in Postmenopausal Women: A Randomized Double-Blinded Placebo-Controlled Clinical Trial. Front Nutr. 2021;8:766711. Published 2021 Dec 24. doi:10.3389/fnut.2021.766711
- Pervez MA, Khan DA, Ijaz A, Khan S. Effects of Delta-tocotrienol Supplementation on Liver Enzymes, Inflammation, Oxidative stress and Hepatic Steatosis in Patients with Nonalcoholic Fatty Liver Disease. Turk J Gastroenterol. 2018 Mar;29(2):170-176. doi: 10.5152/tjg.2018.17297. PMID: 29749323; PMCID: PMC6284694.
- Pervez MA, Khan DA, Slehria AUR, Ijaz A. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial. Complement Ther Med. 2020 Aug;52:102494. doi: 10.1016/j.ctim.2020.102494. Epub 2020 Jun 23. PMID: 32951743.
Geranylgeraniol References
- Source: Nagaoka Y, Kajiya H, Ozeki S, Ikebe T, Okabe K. Mevalonates restore zoledronic acid-induced osteoclastogenesis inhibition. J Dent Res. 2015 Apr;94(4):594-601.
- Source: Chen, X., et al., Geranylgeraniol Restores Zoledronic Acid-Induced Efferocytosis Inhibition in Bisphosphonate-Related Osteonecrosis of the Jaw. Front Cell Dev Biol, 2021. 9: p. 770899.
- Source: Zafar S, et al “Effects of zoledronic acid and geranylgeraniol on angiogenic gene expression in primary human osteoclasts.” J. Oral Science 62 (1):79-83, 2020.
- Source: Koneski F, Popovic-Monevska D, Gjorgoski I, Krajoska J, Popovska M, Muratovska I, Velickovski B, Petrushevska G, Popovski V. In vivo effects of geranylgeraniol on the development of bisphosphonate-related osteonecrosis of the jaws. J Craniomaxillofac Surg. 2018 Feb;46(2):230-236.
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